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Add your own Disease to Dungeons & Dragons Wiki by clicking the link and following the instructions.


5e Diseases

(11 official and unofficial diseases)

DiseaseTargetsIncubationPrimary EffectsSecondary EffectsDamage TypeCarriersSource
Blinding SicknessImmediatepain, reduced Wis checks and savesblindnessSRD5
Bluerot1-4 hoursboils, Con and Cha lossfever, tingling extremities, water breathingundeadGhosts of Saltmarsh
Burrowning Worms1 turnNecrotic damagedeath and rise as the undeadSpawns of KyussVolo's Guide to Monsters
Cackle FeverHumanoids1-4 hoursfever, aches, exhaustionlaughter, incapacitationHumanoidsSRD5
Filth FeverImmediatefeverreduced Str checks, saves, and attack rollsSRD5
Flesh RotImmediateflesh decaydecreased Cha checks, vulnerable to damageSRD5
MindfireImmediatefever of the minddecreased Int checks and saves, confusionSRD5
SeizureImmediateshakingdecreased Dex checks, saves, and attack rollsSRD5
Sewer PlagueHumanoids1-4 daysfatigue, cramps, exhaustionrats, vermin, otyughsSRD5
Sight Rotbeast, humanoid1-4 daysreduced visionblindnessSRD5
Slimy DoomImmediatebleedingdecreased Con checks and saves, stunnedSRD5



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