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An alchemical cannon can be loaded with one or more alchemical item as a move action, although the wielder required to have the items on hand. An Alchemical Cannon can be used a simple weapon two-handed. If a wielder possesses exotic weapon proficiency, she may attach it to their forearm, keeping the hand wielding it free and requiring the other arm simply for aiming.
An Alchemist<sup>Pathfinder</sup> and an Investigator<sup>Pathfinder</sup> gain exotic weapon proficiency with the alchemical cannon in a game with modern technolgy technology being widely available.